abstract |
Various compositions for the treatment of viral infections are disclosed. The composition is a liver-directed antibody construct that comprises an antibody construct that is bound to a bone marrow cell agonist, specifically a TLR7 agonist and a TLR8 agonist, via a linker. Further provided are methods of preparing and using the conjugate. This includes methods of treating viral infections such as viral liver disease. [Selection diagram] Fig. 1 |