http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021506401-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B33Y80-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-2835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00293 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B33Y80-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-32 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12 |
filingDate | 2018-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2021506401-A |
titleOfInvention | Bone substitute material |
abstract | The present invention is a biphasic calcium phosphate / hydroxyapatite (CAP / HAP) bone replacement material that exhibits enhanced bone formation reaction, with a sintered CAP core and nanocrystals deposited on the outer surface of the sintered CAP core. A bone replacement material, comprising a closed epitaxial growth layer of HAP, in which the closed epitaxial growth layer of nanocrystal HAP deposited on the outer surface of a sintered CAP core has a homogeneous coarse outer surface containing flat crystalline platelets. And-the preparation method, the following steps: a) preparing the sintered CAP core material, b) the sintered CAP core material at a temperature between 10 ° C and 0 ° C, ~ 90% short chain fat. Immerse in a buffer containing a group alcohol to initiate the CAP to HAP conversion process, thereby causing a closed epitaxial growth layer of nanocrystal hydroxyapatite on the surface of the sintered CAP core material (where the epitaxial growth nanocrystals are A closed epitaxial growth layer of nanocrystalline HAP formed on the surface of the sintered CAP core material, which has the same size and morphology as human bone mineral) and has a homogeneous rough outer surface containing flat crystalline platelets. C) There is a closed coating of at least one nanocrystal layer of HAP, but the conversion is stopped by separating the solid material from the aqueous solution before the conversion process is complete. , And d), optionally relating to methods involving sterilization of the material separated from step c). |
priorityDate | 2017-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 246.