http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021504711-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2021504711-A |
| titleOfInvention | Anti-drug antibody assay with suppressed target interference |
| abstract | In the present specification, the following steps: a) incubate a serum sample or plasma sample at a pH value which is an approximate pI value of the target, and optionally remove sediment formed after the incubation, b) about 2 Incubate the serum sample or plasma sample obtained in step a) at the pH value of, and optionally, centrifuge the incubated sample to remove the formed precipitate, c) Set the pH value to about. The capture antibody adjusted to 7.4 and conjugated to the first member of the binding pair and the tracer antibody conjugated to a detectable label were added to the serum sample or plasma sample obtained in step b). In addition, the mixture is incubated to form a capture antibody-anti-drug antibody-tracer antibody complex, d) the complex formed in step c) is quantified, thereby in a serum or plasma sample. Anti-drug antibody in a serum sample or plasma sample, which comprises the step of quantifying the amount of the anti-drug antibody (the anti-drug antibody can specifically bind to the drug antibody, and the drug antibody can be used as a therapeutic target. Immunoassays for quantifying the amount of (which can specifically bind) are reported. |
| priorityDate | 2017-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 153.