| abstract |
Equation (I): Substituted furanopyrimidines of chemical constituents (where Ra has any of the values described herein), and compositions containing such chemical constituents; to make them. Methods; and metabolic and rate of response studies; detection and imaging techniques; radiotherapy; modulation and treatment of disorders mediated by PDE1 activity or dopaminergic signaling; neurological disorders, CNS disorders, dementia , Treating neurodegenerative diseases, and trauma-dependent loss of function; treating strokes, including cognitive and movement disorders during stroke rehabilitation; facilitating neuroprotection and nerve recovery; animal skill training protocols To enhance the efficiency of cognitive and exercise training, including; and to include cardiovascular, renal, hematological, gastrointestinal, liver, cancer, infertility, and metabolic disorders. Their use in a wide range of methods, including treating peripheral disorders. |