| abstract |
The present invention provides a 4-1BB antibody and a method and use thereof. Specifically, the invention provides a 4-1BB antibody, which has a high degree of affinity for 4-1BB protein, effectively activates downstream signals of 4-1BB, and human mixed lymphocytes or T cells. IFN-γ and IL-2 expression levels can be significantly increased in, which is useful in the treatment of cancer and autoimmune diseases. |