abstract |
Provided herein are novel homologues (BoNT / EN) of Clostridium Botulinum neurotoxin (BoNT) identified in the bacterial species Enterococcus faecium. BoNT / EN variants and chimeric toxins containing domains from BoNT / EN and other BoNTs are also provided. Further provided herein are methods of producing BoNT / EN, and, by way of example, their use in therapeutic applications. |