| abstract |
PROBLEM TO BE SOLVED: To provide a compound effective for a disease mediated by RORĪ³ such as atopic dermatitis, acne, dermatomyositis, scleroderma, psoriasis, psoriatic arthritis and rheumatoid arthritis, and a pharmaceutical composition. SOLUTION: The pharmaceutical composition contains a compound of the formula XII and the like. [In the formula, A is N or CH; R 1 may be substituted with a halogen atom (C 1 to C 4 ) alkyl, cyclobutyl, cyclopropyl, etc .; L 2 is CH 2 or CHMe; R 6 is. , Halo, -CN, may be substituted with halogen atoms (C 1- C 4 ) alkyl; m is 1 or 2; R 7 is H or CH 2 OH; R 9 is -NH (C 1- C 4 ) Alkyl, or (C 1 to C 4 ) alkyl substituted with OH, etc.] [Selection diagram] None |