| abstract |
PROBLEM TO BE SOLVED: To provide a compound useful as a MALT1 inhibitor and a pharmaceutical composition thereof. Benzyl ((S) -1-((S) -2-(((S) -1-fluoro-6-guanidino-2-oxohexane-3-yl) carbamoyl) pyrrolidine-1-yl)) Provided are compounds such as -3-methyl-1-oxobutane-2-yl) carbamate 2,2,2-trifluoroacetate (Compound 101). Proliferative disorders (eg, cancer (eg, non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, MALT lymphoma), benign neoplasms, angiogenesis-related disorders, autoimmune disorders, inflammatory" due to administration of the compound. Treatment of diseases (diseases, autoinflammatory diseases) is also provided. [Selection diagram] Fig. 3 |