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filingDate 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2021178846-A
titleOfInvention Bendamustine formulation
abstract PROBLEM TO BE SOLVED: To provide a method for treating or preventing cancer or malignant disease using a bendamustine preparation designed for intravenous administration in a small amount. SOLUTION: The method is a solubilizer containing a) about 0.05 to about 12.5 mg / ml of bendamstin or a pharmaceutically acceptable salt thereof, and b) polyethylene glycol and propylene glycol. A solubilizer in which polyethylene glycol is present in an amount of about 0.3 to about 45% by volume and propylene glycol is present in an amount of about 0.03 to about 5% by volume, and optionally c) parenterally acceptable. A liquid composition having a volume of about 325 ml or less containing the diluent to be subjected to is continuously administered to the patient within about 30 minutes. [Selection diagram] None
priorityDate 2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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