abstract |
PROBLEM TO BE SOLVED: To provide a particle containing a conjugate useful for delivering an active agent such as a tumor cytotoxic agent to a cell expressing a somatostatin receptor (SSTR). The conjugate comprises a target ligand and an active agent linked by a linker, and in some embodiments, the conjugate is of formula: (XYZ) (wherein X is a somatostatin receptor). It is a body target portion, where Y is a linker and Z is an active agent). [Selection diagram] Fig. 4 |