http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021172617-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac7a42fad54ea5e8129cbb3716f9540d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate | 2020-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97a1c33dea907c55ea92bd539798c3fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd73ad98d9ec6e863aa71a22da9d58b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33a6155fd6057ed2826ba9a6b558b9fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93204235913ee653fd4445aecf8a814e |
| publicationDate | 2021-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2021172617-A |
| titleOfInvention | Adhesion inhibitor |
| abstract | PROBLEM TO BE SOLVED: To provide a novel postoperative adhesion inhibitor. Specifically, we provide a novel postoperative adhesion inhibitor different from IL-6 receptor antibody and IFN-γ antibody. An adhesion inhibitor containing a substance that inhibits the function of TNFα (Tumor Necrosis Factor α) as an active ingredient is used. According to the adhesion inhibitor, the adhesion score and histologically, the adhesion can be clearly suppressed by the preoperative administration. In addition, administration of the adhesion inhibitor of the present invention also suppresses an increase in the expression level of mRNA of adhesion formation-related molecules such as IL-6 and PAI-1 after surgery. In addition, the expression of inflammatory markers that may occur with adhesions can be suppressed. [Selection diagram] Fig. 1 |
| priorityDate | 2020-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.