| abstract |
PROBLEM TO BE SOLVED: To provide a compound and a method for treating inflammation. The present disclosure relates to compositions and methods for treating inflammatory conditions, including, but not limited to, ocular inflammation, dry eye disease, and ocular neuropathic pain. One aspect of the disclosure relates to a composition comprising (a) a chemerin or a fragment or analog thereof, and (b) a lipid entity linked to the chemerin or a fragment or analog thereof. This lipid entity can be linked to chemerin or a fragment or analog thereof via a linker containing polyethylene glycol, peptide, or a combination thereof. [Selection diagram] None |