| abstract |
PROBLEM TO BE SOLVED: To provide a substance and a method for treating a disease to which treatment with systemamine is indicated. The present invention relates to a disease to which systemamine is indicated, particularly cystine accumulation disease and fatty liver disease. ADO resistant systemamine analogs for use in methods of treating fibrosis, thrombotic disease, MECP-2 related disorders, hereditary mitochondrial diseases, neurological disorders or disorders, inflammation and cancer are targeted. The present disclosure relates to substances and methods for treating diseases for which treatment with cysteamine is indicated. In particular, the disclosure provides therapeutic methods that include administration of the compounds disclosed herein to a patient. [Selection diagram] Fig. 1 |