| abstract |
PROBLEM TO BE SOLVED: To provide an antibody and an antigen-binding fragment against CTLA4 capable of blocking the binding of CTLA4 to its ligand, which can replace ipilimumab, a polynucleotide encoding the same, and a method for using the same. An isolated antibody or antigen-binding fragment thereof comprising a heavy chain CDR sequence selected from the group consisting of a specific sequence. [Selection diagram] None |