| abstract |
PROBLEM TO BE SOLVED: To provide a novel drug which modulates the activity of an immune inhibitory protein such as PD-L1 in consideration of the importance of an immune checkpoint pathway in the regulation of an immune response, thereby activating the immune system. .. An isolated object capable of binding to human programmed death-ligand 1 (PD-L1) in combination with an AKT inhibitor in the manufacture of a medicament for treating cancer or infectious disease in a subject. Provides the use of antibody molecules. [Selection diagram] Fig. 3 |