| abstract |
PROBLEM TO BE SOLVED: To provide an immunomodulatory method and a composition. SOLUTION: A cell containing an exogenous antigen and its use are provided. The present invention is, for example, a method of inducing immune tolerance, which comprises enucleated hematopoietic cells expressing an exogenous antigen in a human subject suffering from or at risk of developing an autoimmune disease, disorder or condition. The pharmaceutical composition is administered in an amount effective to induce immune tolerance in the subject against the antigen that mediates the autoimmune disease, disorder or condition, comprising the step of administering the pharmaceutical composition. Provide a method. [Selection diagram] None |