| abstract |
PROBLEM TO BE SOLVED: To provide a novel active ingredient which can be blended with an external preparation for skin and is useful for promoting extracellular matrix production and preventing or improving thinning of the skin. A pyridine derivative or a pyridine derivative and an ascorbic acid derivative, tranexamic acid or a derivative thereof, hydroquinone or a derivative thereof and kojic acid or a derivative thereof, collagen or a derivative thereof, hyaluronic acid or a derivative thereof, and plants, animals or microorganisms. An external preparation for skin containing any one or more of the derived components. [Selection diagram] None |