abstract |
PROBLEM TO BE SOLVED: To inhibit an inhibitor of tyrosinase, specifically, a composition comprising at least one 2,4-dihydroxybenzene analog which inhibits the activity of tyrosinase and inhibits the overproduction of melanin, such tyrosinase inhibition. Provided are medicinal products, including agents, and methods for producing and using them. SOLUTION: By a compound having the formula IV, or a pharmaceutically acceptable salt thereof. R 1 is H or C 1- C 10 alkyl; R 4 is H, OH or O; R 5 is phenyl, biphenyl, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furanyl, 3-furanyl. or an aromatic ring selected from the group consisting of 2-tetrahydrofuranyl, heteroaromatic or heterocyclic ring; wherein, R 5 is, C 1 -C 10 alkyl group, a C 1 -C 10 alkoxy group or a hydroxyl group Substituted with 1-3 residues independently selected from the group consisting of. [Selection diagram] None |