| abstract |
PROBLEM TO BE SOLVED: To treat an eye disease or disorder of a patient, for example, an eye disease or disorder related to diabetes, a method of treating premature retinopathy of a patient, a wet age-related macular degeneration of a patient. Provide a method of treatment. A therapeutically effective amount of a compound of formula (A) or a composition comprising a tautomer, stereoisomer, geometric isomer, N-oxide or pharmaceutically acceptable salt thereof is administered to a patient. Including doing. [In the formula, X, Y, R 1 , R 2 , R 7 , R 8 , and R 33 represent substituents. ] [Selection diagram] None |