abstract |
PROBLEM TO BE SOLVED: To provide a combination therapy for treating cancer. A combination therapy for the treatment of cancer is provided. The methods of the present disclosure include administration of cyclin-dependent kinase inhibitors and DNA methyltransferase inhibitors to mammals in need thereof. A kit containing instructions for administering a cyclin-dependent kinase inhibitor, a DNA methyltransferase inhibitor, and a cyclin-dependent kinase inhibitor and a DNA methyltransferase inhibitor to a mammal in need of treatment for cancer, and in the methods of the present disclosure. Also provided are useful pharmaceutical compositions. [Selection diagram] None |