| abstract |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for treating cognitive dysfunction or improving cognitive function in a patient who suffers from or is at risk of cognitive dysfunction associated with CNS disorder. The composition comprises a synaptic vesicle protein 2A (SV2A) inhibitor or a pharmaceutically acceptable salt, hydrate, solvate, polymorph, or prodrug thereof, and an acetylcholine esterase inhibitor (AChEI). Or a pharmaceutically acceptable salt, hydrate, solvate, or polymorph or prodrug thereof, wherein the SV2A inhibitor or pharmaceutically acceptable salt, hydrate, solvate thereof. , Polymorphs, or prodrugs are long-term release forms. [Selection diagram] None |