| abstract |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for treating or preventing a B-cell malignant tumor in a subject. A pharmaceutical composition for treating or preventing a B-cell malignant tumor in a subject, which comprises one or more T cells or NK cells containing a vector as an active ingredient, wherein the vector is a chimeric to CD19. The CAR contains a nucleic acid encoding an antigen receptor (CAR), the CAR contains a specific amino acid sequence, and the B-cell malignancies are leukemia, lymphoma, or multiple bone marrow species. [Selection diagram] None |