| abstract |
PROBLEM TO BE SOLVED: To provide a compound useful as a modulator of target-oriented ubiquitination and as an inhibitor thereof with respect to various polypeptides and other proteins. A specific imide compound having a chemical structure: L-CLM, wherein L is a linker group; and CLM is a celebrone E3 ubiquitin ligase binding moiety. A compound in which the linker group is chemically linked to the CLM, or a pharmaceutically acceptable salt thereof, an enantiomer, a stereoisomer, a solvate, or a polymorph. [Selection diagram] Fig. 1 |