Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf522b8b83eded745c73018576219ba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-125 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 |
filingDate |
2020-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1653bdaf046781e2d41a6bd63196680 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66c1b8fb63cf7a42205ae6d3fc7004df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_033e6df48fbe84fb0b5d4552108e50ae |
publicationDate |
2021-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2021000108-A |
titleOfInvention |
Method for producing antigen-specific T cells |
abstract |
PROBLEM TO BE SOLVED: To obtain the same TCR gene rearrangement pattern as an original human T cell in a CD8 single positive cell or a CD4 single positive cell obtained by redifferentiation from a human T cell having antigen specificity via an iPS cell. Provided is a production method for extremely increasing the frequency of appearance of T cells having. A method for producing a human CD8 single positive cell or a CD4 single positive cell having antigen specificity, wherein iPS cells derived from human T cells are differentiated into CD4 / CD8 double negative cells. The step of stimulating the T cell receptor of the CD4 / CD8 double negative cell and the step of differentiating the CD4 / CD8 double negative cell stimulated with the T cell receptor into a CD8 single positive cell or a CD4 single positive cell. Including, method. [Selection diagram] None |
priorityDate |
2012-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |