http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020535805-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2820-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
| filingDate | 2018-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2020535805-A |
| titleOfInvention | Non-integrated DNA vector for gene modification of cells |
| abstract | The present invention relates to the field of gene therapy, exvivo cell therapy, stem cell therapy, and more specifically, self-replicating non-integrated episomal vertebrate expression vectors useful for improving the expression of vector coding antigens or therapeutic genes. Such recombinant DNA molecules are useful in biotechnology, transgenic organisms, gene therapy, stem cell therapy, therapeutic vaccination, agriculture and DNA vaccines. More specifically, with respect to a polynucleotide containing at least one promoter and an S / MAR element, the S / MAR element is located downstream of the promoter and is a nucleic acid sequence (S / MAR sequence) of the S / MAR element. Contains at least three sequence motifs ATTA (SEQ ID NO: 1) per 100 nucleotides over a stretch of up to 200 nucleotides. The present invention further relates to compositions and host cells containing the above polynucleotides, as well as polynucleotides for use in medicine and in the treatment of genetic disorders. The present invention also relates to kits and devices containing the above polynucleotides, as well as methods and uses related to the polynucleotides. [Selection diagram] None |
| priorityDate | 2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 925.