| abstract |
Devices and methods for providing single-use disposable modules or manifolds for bioprocess testing and analysis, as well as portable and compact devices that can be used with modules or manifolds. A module with a valve, a filter or protection column, an affinity column, and a flow cell has several ports for receiving tubing connections for samples and one or more solvents, and one or more. One or more outlet ports for connection to the waste reservoir are provided. Flowing cells may use UV light to determine the protein concentration of a sample in one particular example. The module can be directly or indirectly connected to the bioreactor containing the bioprocess and material to be sampled and can be disposed of once the production process is complete. |