| abstract |
Aminopyrimidine compounds represented by formula (I), polymorphs thereof, pharmaceutically acceptable salts thereof, prodrugs, stereoisomers, isotopic isomers, hydrates or solvates, and solvates thereof. Disclosed pharmaceutical compositions containing, and their use. The aminopyrimidine-based compound and the composition containing this compound have excellent inhibitory properties against protein kinase and also have better pharmacokinetic parameter properties, which increase the drug concentration of the compound in animals. Thereby, the efficacy and safety of the drug can be improved. |