| abstract |
The present invention provides compounds that modulate protein function for restoring protein homeostasis and / or cell-cell adhesion. The present invention provides a method of modulating a protein-mediated disease such as a cytokine-mediated disease, disorder, condition, or response. Compositions of these compounds are also provided. Methods for treating, ameliorating, or preventing protein-mediated diseases, disorders, and conditions are also provided. Also provided is a method of inhibiting the activity of a cytokine, comprising contacting the cell with an effective amount of a compound disclosed herein or a pharmaceutically acceptable salt thereof. |