abstract |
Formula (I), (II) or (III): (In the formula, R 1 , R 2 , R 3 , R 5 , X 1 , X 2 and X 3 are defined herein). The compound having the structure of is an agonist for Toll-like receptor 7 (TLR7) and can be used as an adjuvant for stimulating the immune system. Some of the compounds can be used in conjugates for targeted delivery with respect to the desired effect on target tissue or organ. |