http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020531021-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M27-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 |
| filingDate | 2018-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2020531021-A |
| titleOfInvention | Cell proliferation |
| abstract | 【Task】 A method of proliferating cells in a cell proliferation system is provided. Cells are grown in a bioreactor and activated by an activator (eg, a soluble activator complex). The nutrient supply and gas exchange functions of the automated closed cell proliferation system allow, for example, seeding with low seeding densities. Efficient exchange of nutrients and gas is achieved by manipulating the parameters of the cell growth environment to place cells in specific locations within the bioreactor. System parameters are adjusted to shear cell colonies that may form during the proliferative phase. Metabolic concentrations are controlled to improve cell growth and viability. Cell retention in the bioreactor is controlled. In an embodiment, the cells include T cells. In other embodiments, cells include, for example, T cell subpopulations including regulatory T cells (Tregs) and helpers, naive, memory or effectors. [Selection diagram] FIG. 23 |
| priorityDate | 2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.