http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020528875-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2017-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2020528875-A |
| titleOfInvention | 1- [4-Bromo-5- [1-ethyl-7- (methylamino) -2-oxo-1,2-) for the treatment of cancer associated with genetic abnormalities of platelet-derived growth factor receptor alpha Use of dihydro-1,6-naphthylidine-3-yl] -2-fluorophenyl] -3-phenylurea and amino acids |
| abstract | The present disclosure describes 1- [4-bromo-5- [1-ethyl-7- (methylamino) -2-oxo-1,2-dihydro-1,6-naphthylidine-3-yl] in the treatment of cancer. -2-Fluorophenyl] -3-phenylurea or 1-(5- (7-amino-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthylidine-3-yl) -4-bromo Regarding the use of -2-fluorophenyl) -3-phenylurea. Specifically, the present disclosure describes methods of inhibiting PDGFR kinase, and lung adenomas, squamous cell lung cancer, glial blastoma, pediatric glioma, stellate cell tumor, sarcoma, gastrointestinal stromal tumor, malignant peripheral nerve sheath sarcoma. Inhibition of PDGFR kinase, including intimal sarcoma, eosinophilia syndrome, idiopathic eosinophilia syndrome, chronic eosinophil leukemia, eosinophil acute myeloid leukemia or lymphoblastic T-cell lymphoma Aims at methods of treating cancers and disorders associated with. [Selection diagram] FIG. 1A |
| priorityDate | 2017-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 844.