Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
filingDate |
2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2020-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2020525441-A |
titleOfInvention |
Drug-bearing polymer scaffolds and methods of making protein-polymer-drug conjugates |
abstract |
The present disclosure provides polymeric scaffolds, such as those useful for conjugating protein-based recognition molecules (PBRM) to form PBRM-polymer-drug conjugates, and those PBRM-polymer-drug conjugates. To provide a method of synthesis. The method according to the present disclosure enables large scale preparation of highly pure polymeric scaffolds. In some embodiments, the methods of the present disclosure also allow scaffolds and their conjugates to be prepared in better yields than previously used methods for preparing them. A method of purifying the polymeric scaffold is also disclosed. |
priorityDate |
2017-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |