| abstract |
Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 8 , R 9 , X, X 1 , X 2 , X 3 , L 1 and n are as defined herein. The compound is an inhibitor of adrenomedullin receptor subtype 2 (AM 2 ). Similarly, compounds for use in the treatment of diseases modulated by AM 2 , including proliferative disorders such as cancer, pharmaceutical compositions containing the compounds, methods for preparing the compounds, and the compounds. Intermediates useful for the preparation of are disclosed. |