abstract |
Disclosed herein is a composition comprising a plurality of liposomes having an average diameter of less than 400 nanometers, the plurality of liposomes being: a first lipid or phospholipid; derivatized with a polymer. A second lipid or phospholipid; and a sterically bulky excipient capable of stabilizing liposomes; a third lipid or phospholipid derivatized with a polymer terminated with an integrin targeting moiety; DSPE or contrast enhancing agent A fourth lipid or phospholipid derivatized with a group that binds to, wherein the plurality of liposomes optionally encapsulates a payload component consisting of one or more bioactive agents. |