| abstract |
The present disclosure relates to inhibitors of mitochondrial function. Disclosed are methods of screening compounds for mitochondrial inhibition. In addition, a mitochondrial therapeutic compound having anti-cancer and antibiotic properties, using a mitochondrial inhibitor called mitrivosin, a method for preventing or treating cancer, bacterial infection, and pathogenic yeast, and a mitochondrial inhibitor. Methods of using to provide an anti-aging effect are also described. Also disclosed are specific mitoribosin compounds, and groups of mitoribosin. |