| abstract |
Provided herein are antigen binding proteins (ABPs) that selectively bind to NRP-1 and isoforms and homologs thereof, as well as compositions comprising the above ABPs. Methods (eg, therapeutics and diagnostics) for using the ABPs are also provided. Depletion of regulatory T cells (Tregs) inhibits tumor growth; however, the attendant autoimmune and inflammatory disorders associated with complete depletion of Tregs may limit the clinical utility of this approach. The present specification solves this problem. |