| abstract |
The present invention discloses novel compounds useful as potassium channel openers, especially as Kv7.4 potassium channel openers. Said novel compound is of formula I (wherein n = 0 or 1 and RL is an unsubstituted or substituted cycloalkyl group, in particular a bicycloalkyl group, an unsubstituted or substituted phenyl group, an unsubstituted or substituted thienyl group or a cyclo Selected from the group consisting of a pentathienyl group and an unsubstituted or substituted indanyl group, which optionally contains a heteroatom, and RR is selected from the group consisting of an unsubstituted or substituted phenyl group or an unsubstituted or substituted benzyl group. Which optionally comprises a heteroatom) or stereoisomers, tautomers, prodrugs or salts, preferably pharmaceutically acceptable salts thereof. |