http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020510690-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G73-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-593 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-595 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-59 |
filingDate | 2018-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2020510690-A |
titleOfInvention | Biodegradable drug-polymer conjugate |
abstract | At least one monomer of formula (I): [Where, X may be the same or different at each occurrence, and represents a terminal functional group including alkyne or azide; Q is independently selected at each occurrence, and may or may not be present, and if present, represents a linking group; R is selected from the group consisting of a linear or branched hydrocarbon, an optionally substituted aryl and an optionally substituted heteroaryl, D is a releasable drug selected from prostaglandins, beta-blockers and mixtures thereof, L is a linker group] And at least one comonomer of formula III: J- (YA) n III [J represents a linking functional group, n is from 2 to 8, preferably from 3 to 8, Y comprises a polyether of the formula (OR a ) m wherein R a is independently ethylene, propylene and butylene and m is from 1 to 300 (preferably from 2 to 300), wherein the polyether is And preferably one or more groups selected from one or more of optionally substituted linear or branched C 1 to C 10 alkylene, amino, ether, ester, amide, carbonate and carbamate. And A may be the same or different at each occurrence and represents a group comprising a terminal functional group comprising alkyne or azide functionality, said terminal functional group being complementary to the terminal functional group X of formula (I) , X and A give a triazole moiety] A drug-polymer conjugate that is a copolymer of [Selection diagram] FIG. |
priorityDate | 2017-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 198.