http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020508046-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-902 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-01 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2018-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2020508046-A |
titleOfInvention | Genome editing system and method |
abstract | A Cas9 nuclease variant having higher specificity as compared to a wild-type Cas9 nuclease or an expression construct thereof, and an expression construct comprising a coding sequence of a tRNA-gRNA fusion or a ribozyme-gRNA fusion, or a Cas9 nuclease variant. A genome editing system is provided for site-specifically modifying a target sequence in the genome of a cell, comprising an expression construct comprising both the coding sequence and the coding sequence for a tRNA-gRNA or ribozyme-gRNA. Also provided are methods for genetically modifying cells by introducing a genome editing system with high efficiency and high specificity. |
priorityDate | 2017-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 590.