| abstract |
An antigen comprising a recombinant respiratory syncytial virus (RSV) F protein, wherein said recombinant RSV F protein comprises an antigenic region having both ends in contact with an HRN region and an HRC region, wherein said antigenic region comprises: Disclosed are antigens containing one or more antigenic sites selected from the group consisting of site φ, site II, and site IV. Also disclosed are nucleic acid molecules encoding the antigen, and vaccine compositions comprising the antigen for raising an immune response against RSV. [Selection diagram] FIG. 1A |