| abstract |
Potent 5-HT2B antagonists of Formula (A), including their stereochemically isomeric forms and salts, hydrates, solvates and the like, and potent 5-HT2B antagonists of Formula (A); R1 to R4 and their use, wherein Ar has the meaning as defined herein. The present invention also relates to methods for preparing said compounds, pharmaceutical compositions containing them, use alone or in combination with other agents in the prevention or treatment of fibrosis and / or cirrhosis. Embedded image |