http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020500296-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
filingDate | 2017-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2020500296-A |
titleOfInvention | Nanopore voltage method |
abstract | A method for sequencing nucleic acid molecules comprises nanopores (216) in a membrane (214) present on a well (205), a first electrode (202) below the well, and a second electrode in a chamber (215) on the membrane. Providing a sequencing cell (200) having two electrodes (210) and an electrolyte (206, 208) in a well (205) and a chamber (215). The first electrode (202) is configured to promote non-Faraday conduction of ionic current, forming a capacitance with ions in the electrolyte. A first voltage signal (1310) is applied across the first and second electrodes (202, 210), thereby causing a nucleic acid molecule in the sequencing cell to move through the nanopore (216). Is caused. The first voltage signal (1310) increases during the application of the first voltage signal to compensate for a change in capacitance at the first electrode (202). The method further includes determining a signal value measured during the first voltage signal corresponding to one or more nucleotides in the nucleic acid molecule. |
priorityDate | 2016-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.