| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c58a362565a0616bcc3901fcbf9643de |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-333
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-9789
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08 |
| filingDate |
2020-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98e7734138d7b1d4422276d45ab37c43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e922c66e0abe85db2fe52037f13e9bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1165ddc12473d49de3ec6bfa5c2ff836
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c53a5781764db4b228cdde8e1abc79b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3664edb657ea4baa823f268a6437b8cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc6f6a99f5505744e0525f3124982ae4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc5cabc7e7c2a7593247c5b827df9424
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1797782854cf7b15e945fb40c9d2e2ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2906af231f221d48ab1e299d6956817 |
| publicationDate |
2020-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2020189840-A |
| titleOfInvention |
How to treat cellular senescence |
| abstract |
PROBLEM TO BE SOLVED: To provide an alcohol extract of Ajuga decumbens from Taiwan. The present invention provides an alcoholic extract of Ajuga decumbens from Taiwan. The alcohol extract of Ajuga decumbens was found to have a significant effect on inhibiting the aging of human WI-38 lung fibroblasts and human skin fibroblasts. Furthermore, it was found that the alcohol extract of Ajuga decumbens inhibits the expression of cofilin-1 and that cofilin-1 is a protein involved in actin dynamics (actin dynamics) and cell morphology and is increased in senescent cells. Was done. The inhibitory effect of this plant extract on cell senescence is more effective at low concentrations without excessively inhibiting cell viability and growth. [Selection diagram] Fig. 1 |
| priorityDate |
2019-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |