abstract |
PROBLEM TO BE SOLVED: To provide a method for producing a 5,7-difluorochroman-4-one derivative. SOLUTION: 3,5-Difluorophenol is reacted with 3-halogenated propanol and has the following chemical formula. The first step of producing the compound represented by, the second step of reacting the compound with 2-iodobenzoic acid and potassium peroxymonosulfate, and further, a cyclization reaction. A method for producing a 5,7-difluorochroman-4-one derivative represented by the following chemical formula, which comprises a third step. [Selection diagram] None |