abstract |
PROBLEM TO BE SOLVED: To provide a method for preventing, reducing or eliminating the occurrence of male androgen deficiency symptoms or diseases including male hypogonadism-related symptoms and diseases due to low testosterone and / or low peripheral androgen formation. SOLUTION: A method for preventing, reducing or eliminating the occurrence of male androgen deficiency symptoms or diseases including male gonad dysfunction-related symptoms and diseases, for male patients in need of the prevention, reduction or elimination. By a method comprising administering a therapeutically effective amount of a sex steroid precursor or a prodrug thereof in association with a therapeutically effective amount of a selective estrogen receptor modulator or anti-estrogen drug or any prodrug. Solve the problem. [Selection diagram] Fig. 1 |