| abstract |
PROBLEM TO BE SOLVED: To provide a multi-component dosage form in which one component contains tenofovir DF and, if necessary, emtricitabine, and the other component contains at least efavirenz. According to the present invention, a novel pharmaceutical product containing efavirenz, emtricitabine, and tenofovir DF, in which component 1 contains tenofovir DF (and, if necessary, emtricitabine) and component 2 contains efavirenz. It is provided as a body-type oral dosage form in which components 1 and 2 are in a stabilized arrangement. In a preferred embodiment, component 1 is produced by dry granulation. Provided is a composition comprising tenofovir DF and a surfactant, wherein the surfactant is in a stabilized arrangement with tenofovir DF. [Selection diagram] None |