| abstract |
PROBLEM TO BE SOLVED: To insulin receptor such as type 1 diabetes, dyslipidemia, hyperglycemia, hypoglycemia, impaired glucose tolerance, HIV / HAART-induced partial lipodystrophy, metabolic syndrome, non-alcoholic fatty liver disease (NAFLD), etc. Providing a method for treating a disorder (INSR disorder). A method comprising administering to a patient with an INSR disorder a therapeutically effective amount of (a) an isolated human FGF21 polypeptide; or (b) a FGF21 protein variant. It is preferred that the FGF21 protein variant is mutant 76 or an Fc fusion protein. [Selection diagram] None |