| abstract |
PROBLEM TO BE SOLVED: To provide a compound for use in the treatment, prevention or management of a disease associated with activation, mutation and / or overexpression of a kinase. When a disease associated with kinase activation, mutation and / or overexpression is associated with Axl overexpression, the disease is associated with activation, mutation and / or overexpression of one or more other kinases. Also associated with 1- (6,7-dihydro-5H-benzo [6,7] cyclohepta [1,2-c] pyridazine-3-yl) for use in the treatment, prevention or management of the disease. -N3- (7- (Pyridazine-1-yl) -6,7,8,9-tetrahydro-5H-benzo [7] annulene-2-yl) -1H-1,2,4-triazole-3,5 -A compound having a specific chemical structure represented by diamine is provided. [Selection diagram] Fig. 1 |