| abstract |
PROBLEM TO BE SOLVED: To provide a novel compound having an activity as an inhibitor of ALK2 and/or JAK2 kinase, and a method of using the same for treating various cancers. SOLUTION: 2-(3-((5-chloro-2-((3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidine-4 represented by the following structural formula. Compounds typified by -yl)amino)phenyl)acetonitrile, and methods for use, and pharmaceutical compositions containing such compounds. [Selection diagram] None |