abstract |
PROBLEM TO BE SOLVED: To provide an improved interferon therapy. The present invention provides a method for improving the efficacy of interferon as a human therapeutic agent, the method comprising: a. Diagnosing a condition that can be treated with interferon in a human patient, and then b. The step of administering to said human a second agent that inhibits an inhibitory human immune system checkpoint, said agent being in an amount sufficient to reduce the activity of said checkpoint with respect to reducing immune activity. Administering c., c. Administering to the human a first agent that increases interferon levels in the human patient in an amount effective to treat the condition. [Selection diagram] Figure 1 |